Curzate M8 Fungicide (Cymoxanil 8% + Mancozeb 64% WP)
The "First Strike" Curative Solution for Late Blight and Downy Mildew.
Curzate M8 by Corteva Agriscience is a specialized fungicide designed to save crops even after infection has started. Unlike standard protective sprays, Curzate M8 works inside the plant to stop disease spread. It combines the deep-cleaning power of Cymoxanil with the protective shield of Mancozeb.
Best For: Farmers facing sudden disease outbreaks during cloudy or rainy weather who need an immediate "kick-back" cure.
Why Choose This Product? Key Benefits
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Curative "Kick-Back" Action: Unique ability to heal the plant and stop infection even if applied 24 to 72 hours (1-3 days) after the disease strikes.
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Dual-Action Protection: Provides a protective layer on the outside (Mancozeb) while cleaning the fungus from the inside (Cymoxanil).
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Rapid Absorption: Penetrates the leaf surface in less than 3 hours, ensuring the medicine starts working fast.
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Rainfastness: Excellent for monsoon seasons. Once absorbed (approx. 3 hours), it cannot be washed off by rain.
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Stops Spore Spread: Actively suppresses the production of new spores, preventing the disease from jumping to healthy plants.
Technical Specifications
| Parameter | Details |
|---|---|
| Brand Name | Curzate M8 |
| Technical Name | Cymoxanil 8% + Mancozeb 64% WP |
| IRAC MoA Code | Group 27 (Cymoxanil) + Group M03 (Mancozeb) |
| Chemical Group | Cyanoacetamide oxime + Dithiocarbamate |
| Formulation | Wettable Powder (WP) |
| Toxicity Label | Blue/Yellow Triangle (Moderate Toxicity) |
How It Works: Mode of Action
Curzate M8 uses a "Triple Defense" mechanism to ensure complete control over Oomycete fungi:
- Contact Prevention (Mancozeb): When sprayed, it forms a coating on the leaf. If a fungus spore lands, it is killed instantly before it can enter the plant.
- Curative Penetration (Cymoxanil): If the fungus has already entered the leaf (within the last 1-3 days), Cymoxanil penetrates the tissue and kills the hidden infection (the "kick-back" effect).
- Antisporulant Action: It stops existing disease spots from producing new spores, slowing down the spread of the disease in the field.
Note: Cymoxanil is locally systemic (translaminar), meaning it moves across the leaf but not throughout the whole plant. Good coverage is essential.
Target Crops & Pests
| Crop | Target Pest(s) |
|---|---|
| Potato | Late Blight (Phytophthora infestans) |
| Grapes | Downy Mildew (Plasmopara viticola) |
| Tomato | Late Blight (Phytophthora infestans) |
Dosage & Application Guide
The Golden Rule: Always follow the "Dose per Acre" for accurate results.
Dosage per Acre, Litre, & Pre-Harvest Interval (PHI)
| Crop | Dose (g / Acre) | Water (L / Acre) | Dose (g / Litre) | PHI (Days) |
|---|---|---|---|---|
| Potato | 600 g | 200 L | 3 g | Refer Label |
| Grapes | 600 - 800 g | 200 - 300 L | 2 - 2.5 g | 66 Days* |
| Tomato | 600 g | 200 L | 3 g | Refer Label |
*PHI = Pre-Harvest Interval: The minimum number of days to wait between the last spray and harvesting. Note for Grape Exporters: Do not use Curzate M8 after fruit setting due to strict residue limits (66 days PHI).
How to Apply: Best Practices
- Timing: Apply preventively when weather is cloudy/humid, or immediately (within 1-3 days) if you see disease symptoms.
- Mixing: This is a Wettable Powder (WP). Make a slurry (thick paste) with a little water first, then add it to the main tank while stirring. Keep the water agitated.
- Coverage: Ensure full coverage of the leaves. For grapes, spray carefully to reach the underside of leaves where Downy Mildew hides.
- Safety: Always wear PPE (gloves, mask, goggles). Wash hands thoroughly after use. Avoid mixing with highly alkaline substances like Bordeaux mixture.
Frequently Asked Questions
1. Can Curzate M8 cure disease that has already started?
Yes. Thanks to Cymoxanil, it has a "kick-back" action that can stop infection if applied within 24-72 hours of the disease starting.
2. Is this product safe for export grapes?
Only if used in the early stages (vegetative/pre-flowering). It has a long waiting period (PHI) of 66 days, so do not use it after the berries have formed.
3. Can I mix Curzate M8 with insecticides?
Yes, it is generally compatible with common insecticides like Imidacloprid and Chlorpyrifos for controlling sucking pests along with blight.
4. How soon can it rain after spraying?
Curzate M8 is absorbed into the leaf within 3 hours. If it rains after 3 hours, you do not need to re-spray.
5. What is the recommended spray interval?
Under normal conditions, spray every 10–14 days. If disease pressure is high (continuous rain/humidity), reduce the gap to every 5–7 days.
Safety & Disclaimer
Always read and follow the instructions on the official product label. The information provided here is for guidance only. Use personal protective equipment (PPE) during application.

